Aortic dissection detection risk score has high sensitivity with moderate inter-rater reliability

Abstract

Objective: To retrospectively assess the accuracy and inter-rater reliability of the aortic dissection detection risk score (ADD-RS). Methods: Single-centre, observational, diagnostic accuracy study undertaken in a university-affiliated, tertiary hospital ED. Results: Two hundred patients were enrolled. Five patients were diagnosed with acute aortic dissection and had an elevated ADD-RS >0. The ADD-RS was 100% sensitive with a negative and positive predictive values of 100% (if ADD-RS ≥1). Inter-rater reliability was moderate (Kappa = 0.55). Conclusion: The ADD-RS was highly sensitive in our cohort. Further work to evaluate the score prospectively and in combination with a D-Dimer is require..