Importance of bioavailable calcium in fluoride dentifrices for enamel remineralization
Peiyan Shen, Glenn D Walker, Yi Yuan, Coralie Reynolds, David P Stanton, James R Fernando, Eric C Reynolds
JOURNAL OF DENTISTRY | ELSEVIER SCI LTD | Published : 2018
OBJECTIVES: To compare remineralization of enamel subsurface lesions by fluoride dentifrices with added calcium in a double-blind, randomized, cross-over, in situ study. METHODS: Human enamel with subsurface lesions were prepared and inserted into intra-oral appliances worn by volunteers. A slurry (1 g toothpaste/4 ml H2O) was rinsed for 60 s, 4 times per day for 14 days. Seven toothpastes were tested: (i) 1450 ppm F (NaF), (ii) 5000 ppm F (NaF), (iii) 1450 ppm F (MFP) with calcium sodium phosphosilicate (CSP), (iv) 1450 ppm F (MFP) with CaCO3/Arg, (v) 1150 ppm F (SnF2) with amorphous calcium phosphate (ACP), (vi) 1100 ppm F (NaF) with casein phosphopeptide-amorphous calcium phosphate (CPP-A..View full abstract
Awarded by Australian Government Department of Industry, Innovation and Science grant
This study was supported by the Australian Government Department of Industry, Innovation and Science grant 20080108.