Plasmepsin V cleaves malaria effector proteins in a distinct endoplasmic reticulum translocation interactome for export to the erythrocyte

Danushka S Marapana; Laura F Dagley; Jarrod J Sandow; Thomas Nebl; Tony Triglia; Michal Pasternak; Benjamin K Dickerman; Brendan S Crabb; Paul R Gilson; Andrew Webb; Justin A Boddey; Alan F Cowman

Journal article

Plasmepsin V cleaves malaria effector proteins in a distinct endoplasmic reticulum translocation interactome for export to the erythrocyte

Danushka S Marapana, Laura F Dagley, Jarrod J Sandow, Thomas Nebl, Tony Triglia, Michal Pasternak, Benjamin K Dickerman, Brendan S Crabb, Paul R Gilson, Andrew Webb, Justin A Boddey, Alan F Cowman

Nature Microbiology | NATURE PUBLISHING GROUP | Published : 2018

DOI: 10.1038/s41564-018-0219-2

University of Melbourne Researchers

Brendan Crabb Author Microbiology and Immunology

Andrew Webb Author Medical Biology (W.E.H.I.)

Laura Dagley Author Medical Biology (W.E.H.I.)

Alan Cowman Author Medical Biology (W.E.H.I.)

Jarrod Sandow Author Medical Biology (W.E.H.I.)

Grants

Awarded by EMBO

Funding Acknowledgements

We thank the Red Cross Blood Service (Melbourne, Victoria, Australia) for the supply of donor blood for our cell culture. This work was supported by the NHMRC of Australia and the Victorian State Government Operational Infrastructure Support and the Australian Government NHMRC IRIISS. A.F.C. is a Howard Hughes International Scholar. M.P. was supported by the EMBO Long-Term Fellowship ALTF 793-2016.