Ga-labeled Prostate-specific Membrane Antigen Ligand-positron-emission Tomography: Still Just the Tip of the Iceberg

Abstract

Objectives: To assess the performance of Ga-labeled prostate-specific membrane antigen ligand-positron-emission tomography (Ga-PSMA PET) for positive lymph nodes on imaging after curatively intended radical prostatectomy. Patients and Methods: Seventeen patients with biochemical recurrence after radical prostatectomy undergoing robot-assisted salvage lymphadenectomy for positive lymph nodes on imaging were included in this single surgeon study. The performance of Ga-PSMA PET was assessed on per patient, per lesion, per landing site and per laterality level using sensitivity, specificity, and negative and positive predictive value analysis. Results: A total of 34 positive nodes were detected ..