Journal article

Aerobic Exercise Improves Cognitive Functioning in People With Schizophrenia: A Systematic Review and Meta-Analysis

Joseph Firth, Brendon Stubbs, Simon Rosenbaum, Davy Vancampfort, Berend Malchow, Felipe Schuch, Rebecca Elliott, Keith H Nuechterlein, Alison R Yung



Cognitive deficits are pervasive among people with schizophrenia and treatment options are limited. There has been an increased interest in the neurocognitive benefits of exercise, but a comprehensive evaluation of studies to date is lacking. We therefore conducted a meta-analysis of all controlled trials investigating the cognitive outcomes of exercise interventions in schizophrenia. Studies were identified from a systematic search across major electronic databases from inception to April 2016. Meta-analyses were used to calculate pooled effect sizes (Hedges g) and 95% CIs. We identified 10 eligible trials with cognitive outcome data for 385 patients with schizophrenia. Exercise significant..

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University of Melbourne Researchers


Awarded by German Federal Ministry of Education and Research

Awarded by Medical Research Council

Funding Acknowledgements

J.F. is funded by an MRC Doctoral Training Grant. D.V. is funded by the Research Foundation - Flanders (FWO-Vlaanderen). S.R. is funded by a Society for Mental Health Research Early Career Fellowship (Australia). K.H.N. is funded by NIMH, Janssen, Stanley Medical Research Institute, and Posit Science. B.M. is funded by the German Federal Ministry of Education and Research (BMBF: 01EE1407AE).