Self-reported cognitive function in a large international cohort of people with multiple sclerosis: associations with lifestyle and other factors
PL Jelinek, S Simpson, CR Brown, GA Jelinek, CH Marck, AM De Livera, E O'Kearney, KL Taylor, SL Neate, TJ Weiland
EUROPEAN JOURNAL OF NEUROLOGY | WILEY | Published : 2019
BACKGROUND AND PURPOSE: We aimed to estimate the prevalence of perceived cognitive impairment (PCI) and explore its associations with lifestyle and disease characteristics in a large international cohort of people with multiple sclerosis (MS). METHODS: This study was a cross-sectional analysis. Participants rated their cognitive function over the preceding 4 weeks using four questions in a subscale within the Multiple Sclerosis Quality of Life questionnaire (MSQOL-54). These questions assessed perceived concentration, attention and memory by the patient and family/friends. Four definitions of PCI were derived, ranging from lowest to highest specificity. Associations with PCI were assessed by..View full abstract
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Awarded by Early Career Fellowship from the National Health and Medical Research Council
The authors thank all of the participants in the HOLISM study for taking the survey and the Bloom Foundation, Wal Pisciotta and the Horne Family Charitable Trust for supporting this study.The study was funded by the Bloom Foundation, Wal Pisciotta and the Horne Family Charitable Trust. C.H.M. is funded by an Early Career Fellowship from the National Health and Medical Research Council (ID 1120014). Funding was received from The Royal Australian and New Zealand College of Psychiatrists, New Investigator Grant (K.L.T.).