Journal article

Nanoengineering of Poly(ethylene glycol) Particles for Stealth and Targeting

Jiwei Cui, Mattias Bjornmalm, Yi Ju, Frank Caruso

LANGMUIR | AMER CHEMICAL SOC | Published : 2018

Abstract

The assembly of particles composed solely or mainly of poly(ethylene glycol) (PEG) is an emerging area that is gaining increasing interest within bio-nano science. PEG, widely considered to be the "gold standard" among polymers for drug delivery, is providing a platform for exploring fundamental questions and phenomena at the interface between particle engineering and biomedicine. These include the targeting and stealth behaviors of synthetic nanomaterials in biological environments. In this feature article, we discuss recent work in the nanoengineering of PEG particles and explore how they are enabling improved targeting and stealth performance. Specific examples include PEG particles prepa..

View full abstract

Grants

Awarded by Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology


Awarded by National Health and Medical Research Council Senior Principal Research Fellowship


Awarded by National Natural Science Foundation of China


Awarded by Horizon 2020 (European Union) through a Marie Sklodowska-Curie Individual Fellowship


Funding Acknowledgements

This work was conducted and funded by the Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology (project number CE140100036). F.C. acknowledges the award of a National Health and Medical Research Council Senior Principal Research Fellowship (APP1135806). J.C. acknowledges the Recruitment Program of Global Experts and the National Natural Science Foundation of China (no. 21603120). M.B. acknowledges support from Horizon 2020 (European Union) through a Marie Sklodowska-Curie Individual Fellowship under grant agreement no. 745676.