Ensemble Properties of Bax Determine Its Function

Adeline Y Robin; Sweta Iyer; Richard W Birkinshaw; Jarrod Sandow; Ahmad Wardak; Cindy S Luo; Melissa Shi; Andrew Webb; Peter E Czabotar; Ruth M Kluck; Peter M Colman

Journal article

Ensemble Properties of Bax Determine Its Function

Adeline Y Robin, Sweta Iyer, Richard W Birkinshaw, Jarrod Sandow, Ahmad Wardak, Cindy S Luo, Melissa Shi, Andrew Webb, Peter E Czabotar, Ruth M Kluck, Peter M Colman

Structure | CELL PRESS | Published : 2018

DOI: 10.1016/j.str.2018.07.006

University of Melbourne Researchers

Peter Czabotar Author Medical Biology (W.E.H.I.)

Andrew Webb Author Medical Biology (W.E.H.I.)

Sweta Iyer Author Medical Biology (W.E.H.I.)

Jarrod Sandow Author Medical Biology (W.E.H.I.)

Adeline Robin Author Medical Biology (W.E.H.I.)

Grants

Funding Acknowledgements

Studies supported by grants and fellowships from the NHMRC, the Australian Cancer Research Foundation, the Leukemia and Lymphoma Society (US), Lady Tata Memorial Trust, and the Victorian State Government Operational Infrastructure Support and the Australian Government NHMRC IRIIS. We thank Tony Burgess, Shenggen Yao, Jeff Babon, Matthew Call, and Grant Dewson for discussions, and Robert Ninnis for input into the HDX-MS analysis. Crystallization experiments were performed at the CSIRO C3 Crystallisation Center, and diffraction data were collected at the Australian Synchrotron.