Journal article

Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU

John W Devlin, Yoanna Skrobik, Celine Gelinas, Dale M Needham, Arjen JC Slooter, Pratik P Pandharipande, Paula L Watson, Gerald L Weinhouse, Mark E Nunnally, Bram Rochwerg, Michele C Balas, Mark van den Boogaard, Karen J Bosma, Nathaniel E Brummel, Gerald Chanques, Linda Denehy, Xavier Drouot, Gilles L Fraser, Jocelyn E Harris, Aaron M Joffe Show all

Critical Care Medicine | LIPPINCOTT WILLIAMS & WILKINS | Published : 2018

University of Melbourne Researchers


Awarded by National Institutes of Health (NIH)

Funding Acknowledgements

Dr. Devlin has received research funding from the National Institute of Aging, National Heart, Lung and Blood Institute, and AstraZeneca Pharmaceuticals, he is on the editorial board of Critical Care Medicine, and he is the president of the American Delirium Society. Dr. Skrobik participates in the ATS and the American College of Chest Physicians (ACCP), and she is on the editorial board for Intensive Care Medicine and Chest. Dr. Needham is a principal investigator on a National Institutes of Health (NIH)-funded, multicentered randomized trial (R01HL132887) evaluating nutrition and exercise in acute respiratory failure and, related to this trial, is currently in receipt of an unrestricted research grant and donated amino acid product from Baxter Healthcare and an equipment loan from Reck Medical Devices to two of the participating study sites, external to his institution. Dr. Slooter has disclosed that he is involved in the development of an electroencephalogram-based delirium monitor, where any (future) profits from electroencephalogram-based delirium monitoring will be used for future scientific research only. Dr. Pandharipande's institution received funding from Hospira (research grant to purchase study drug [dexmedetomidine] in collaboration with a NIH-funded RO1 study) and disclosed that he is the past president of the American Delirium Society. Dr. Nunnally participates in the Society of Critical Care Anesthesiologists, International Anesthesia Research Society, and American Society of Anesthesiology (ASA). Dr. Rochwerg participates as a guideline methodologist for other organizations (i.e., American Thoracic Society [ATS] and Canadian Blood Service) in addition to the Society of Critical Care Medicine. Dr. Balas received funding from Select Medical (primary investigator on research study exploring Assess, Prevent, and Manage Pain, Both Spontaneous Awakening Trials and Spontaneous Breathing Trials, Choice of analgesia and sedation, Delirium: Assess, Prevent, and Manage, Early mobility and Exercise, and Family engagement and empowerment bundle adoption). Dr. Bosma received funding from the Canadian Institutes of Health Research (CIHR) where she is the primary investigator of an industry partnered research grant with Covidien as the industry partner of the CIHR for a study investigating proportional assist ventilation versus pressure support ventilation for weaning from mechanical ventilation. Dr. Brummel participates in the ATS (Aging and Geriatrics Working Group Co-Chair) and ArjoHuntleigh (advisory board activities). Dr. Chanques participates in other healthcare professional organization activities. Dr. Denehy participates in the Australian Physiotherapy Association. Dr. Drouot participates in the French Sleep Society and the French Institute for Sleep and Vigilance. Mr. Joffe participates on committees for ASA. Dr. Kho received funding from Restorative Therapies (Baltimore, MD) (loaned two supine cycle ergometers for ongoing research). Dr. Kress received funding from a dexmedetomidine speaker program, he participates in the ATS and ACCP, and he has served as an expert witness in medical malpractice. Dr. McKinley participates in the American Association of Critical-Care Nurses (AACN) (editorial board of American Journal of Critical Care) and the American Heart Association (editorial board of Journal of Cardiovascular Nursing). Dr. Neufeld participates in the American Delirium Society (board member). Dr. Pisani participates in the ACCP (Chair Scientific Programming Committee and Steering Committee Women's Health Network). Dr.r Payen received funding from Baxter SA (distributor of dexmedetomidine in France), and he has received honorariums from Baxter SA (oral presentations of dexmedetomidine). Ms. Pun participates as an AACN speaker at the National Conference. Dr. Puntillo participates in other healthcare professional organizations (e.g., AACN). Dr. Robinson participates in the Easter Association for the Surgery of Trauma, American College of Surgeons, and American Association for the Surgery of Trauma. Dr. Shehabi received funding from an unrestricted research grant (drug supply) from Pfizer (Hospira) and Orion Pharma to an ongoing multi-national multicenter study. Mr. Szumita participates in several committees for the American Society of Health-System Pharmacists. Ms. Price has disclosed that she is a medical librarian working at Johns Hopkins University, and she consults as an information specialist to the Cochrane Urology Review Group. Dr. Flood participates on the Society of Obstetric Anesthesia and Perinatology research committee and the ASA Chronic Pain Committee. The remaining authors have disclosed that they do not have any potential conflicts of interest.