Myocardial tissue characterisation and detection of myocardial oedema by cardiovascular magnetic resonance in women with pre-eclampsia: a pilot study
SMM Chen, L Leeton, JM Castro, AT Dennis
INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA | ELSEVIER SCI LTD | Published : 2018
BACKGROUND: Pre-eclampsia is characterised by increased left ventricular wall thickness on transthoracic echocardiography (TTE). This is assumed to be myocardial hypertrophy, however TTE cannot determine myocardial structure which may be muscle, oedema or fibrosis. Given the high incidence of peripheral oedema in pre-eclampsia, we hypothesised that increased thickness could represent oedema. Cardiovascular magnetic resonance (CMR) characterises myocardial tissue, differentiating between hypertrophy, oedema and fibrosis. This pilot study was designed to characterise myocardial composition using CMR in pregnant women (healthy or with pre-eclampsia) and to compare cardiac output and left ventri..View full abstract
This study was funded by a project grant from The Australian and New Zealand College of Anaesthetists (ANZCA) Mundipharma Research Award.