Porous Inorganic and Hybrid Systems for Drug Delivery: Future Promise in Combatting Drug Resistance and Translation to Botanical Applications
Junling Guo, Bruno D Mattos, Blaise L Tardy, Vanessa M Moody, Gao Xiao, Hirotaka Ejima, Jiwei Cui, Kang Liang, Joseph J Richardson
Current Medicinal Chemistry | Bentham Science Publishers | Published : 2019
Background: Porous micro- and nanoparticles have the capacity to encapsulate a large quantity of therapeutics, making them promising delivery vehicles for a variety of applications. This review aims to highlight the latest development of inorganic and hybrid (inorganic/ organic) particles for drug delivery with an additional emphasis on combatting drug resistant cancer. We go one step further and discuss delivery applications beyond medicinal delivery, as there is generally a translation from medicinal delivery to botanic delivery after a short lag time. Methods: We undertook a search of relevant peer-reviewed publications. The quality of the relevant papers was appraised using standard tool..View full abstract
Awarded by National Natural Science Foundation of China
Awarded by Fundamental Research Funds of Shandong University
Awarded by J.S.P.S.
This work was supported by the National Natural Science Foundation of China (21603120) and the Fundamental Research Funds of Shandong University (2017JC003). Jiwei Cui acknowledges the Thousand Talents Plan Program of China.Joseph J. Richardson acknowledges J.S.P.S. funding project ID PE17019.