Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells
Cedric S Tremblay, Jesslyn Saw, Sung Kai Chiu, Nicholas C Wong, Kirill Tsyganov, Sarah Ghotb, Alison N Graham, Feng Yan, Andrew A Guirguis, Stefan E Sonderegger, Nicole Lee, Paul Kalitsis, John Reynolds, Stephen B Ting, David R Powell, Stephen M Jane, David J Curtis
Nature Communications | NATURE PUBLISHING GROUP | Published : 2018
Awarded by Australian National Health and Medical Research Council (NHMRC)
We thank Geza Paukovics, Jeanne LeMasurier, Eva Orlowski-Oliver and Phil Donaldson from the AMREP Flow Cytometry Facility for assistance with flow cytometry. We also thank Stephen Cody and Iska Carmichael from the Monash Micro Imaging platform as well as Shilpa Bereeka and Loretta Cerruti for technical assistance. We thank Associate Professor Steven Lane from the QIMR Berghofer, Professor Sarah Russell and Dr Mirren Charnley from the Peter MacCallum Cancer Centre and the Centre for Micro-Photonics of the Swinburne University of Technology, as well as Dr Ian Majewski and Dr Kim Pham from the Walter and Eliza Hall Institute for Medical Research (WEHI) for assistance with experimental design and intellectual input. This work was supported by Project Grants (1052313 (to D.J.C.), 1047554 (to S.B.T.)) and a Career Development Fellowship (1047630 (to S.B.T.)) from the Australian National Health and Medical Research Council (NHMRC), and a Senior Medical Research Fellowship from the Sylvia and Charles Viertel Foundation (to D.J.C.).