Outcome of Treatment of Uveitic Macular Edema: the Multicenter Uveitis Steroid Treatment Trial 2-Year Results

O Tomkins-Netzer; S Lightman; L Drye; J Kempen; GN Holland; NA Rao; RJ Stawell; A Vitale; DA Jabs; GJ Jaffe; B Branchaud; P Hahn; L Koreen; EN Lad; P Lin; JN Martel; NS Serrano; C Skalak; L Vajzovic; C Baer; J Bryant; S Chavala; M Cusick; S Day; P Dayani; J Ehlers; M Kesen; A Lee; A Melamud; JA Qureshi; AW Scott; RF See; RK Shuler; M Wood; S Yeh; A Fernandes; D Gibbs; D Leef; DF Martin; S Srivastava; JP Dunn; H Begum; J Boring; KL Brotherson; B Burkholder; NJ Butler; D Cain; MA Cook; D Emmert; JR Graul; M Herring; A Laing; TG Leung; MC Mahon; A Moradi; A Nwankwo; TL Ostheimer; T Reed; E Arnold; PM Barnabie; ML Belair; SG Bolton; JB Brodine; DM Brown; LM Brune; A Galor; T Gan; A Jacobowitz; M Kapoor; S Kedhar; S Kim; HA Leder; AG Livingston; Y Morton; K Nolan; GB Peters; P Soto; R Stevenson; M Tarver-Carr; Y Wang; C Foster; SD Anesi; L Bruner; O Ceron; DM Hinkle; N Persons; B Wentworth; S Acevedo; F Anzaar; T Cesca; A Contero; K Fitzpatrick; F Goronga; J Johnson; KQ Lebron; D Marvell; C Morgan; N Patel; J Pinto; SS Siddique

Journal article

Outcome of Treatment of Uveitic Macular Edema: the Multicenter Uveitis Steroid Treatment Trial 2-Year Results

O Tomkins-Netzer, S Lightman, L Drye, J Kempen, GN Holland, NA Rao, RJ Stawell, A Vitale, DA Jabs, GJ Jaffe, B Branchaud, P Hahn, L Koreen, EN Lad, P Lin, JN Martel, NS Serrano, C Skalak, L Vajzovic, C Baer Show all

Ophthalmology | ELSEVIER SCIENCE INC | Published : 2015

DOI: 10.1016/j.ophtha.2015.07.036

Abstract

Purpose To evaluate the 2-year outcomes of uveitic macular edema. Design Longitudinal follow-up of a randomized cohort. Participants At baseline, 148 eyes of 117 patients enrolled in the Multicenter Uveitis Steroid Treatment (MUST) Trial had macular edema, and 134 eyes of 108 patients completed 2-year follow-up. Methods Patients enrolled in the study were randomized to either systemic immunosuppression or intravitreal fluocinolone acetonide implant therapy. Macular edema was defined as thickening of the retina (center point thickness ≥240 μm) on time-domain optical coherence tomography (OCT) of macula. Main Outcome Measures Improvement in macular edema (≥20% reduction in central point thickn..

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University of Melbourne Researchers

Lyndell Lim Author

Grants

Awarded by National Institutes of Health

Funding Acknowledgements

Supported in part by cooperative agreements U10 EY 014655 to the Icahn School of Medicine at Mount Sinai, U10 EY 014660 to the Johns Hopkins University Bloomberg School of Public Health, and U10 EY 014654 to the University of Wisconsin, Madison, from the National Eye Institute, the National Institutes of Health, Bethesda, Maryland.