Journal article

Laboratory Diagnosis of Neurocysticercosis (Taenia solium).

Hector H Garcia, Seth E O'Neal, John Noh, Sukwan Handali, undefined Cysticercosis Working Group in Peru

Journal of Clinical Microbiology | Published : 2018

Abstract

Neurocysticercosis accounts for approximately 30% of all epilepsy cases in most developing countries. The immunodiagnosis of cysticercosis is complex and strongly influenced by the course of infection, the disease burden, the cyst location, and the immune response of the host. The main approach to immunodiagnosis should thus be to evaluate whether the serological results are consistent with the diagnosis suggested by imaging. Antibody detection is performed using lentil lectin-purified parasite antigens in an enzyme-linked immunoelectrotransfer blot format, while antigen detection uses a monoclonal antibody-based enzyme-linked immunosorbent assay (ELISA). Promising new assay configurations h..

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University of Melbourne Researchers