Journal article

A healthy dietary pattern associates with a lower risk of a first clinical diagnosis of central nervous system demyelination

Lucinda J Black, Charlotte Rowley, Jill Sherriff, Gavin Pereira, Anne-Louise Ponsonby, Robyn M Lucas, Jeffrey Blackie, Richard Bourke, John Cameron, Ross Carne, Ben Clark, Steven Collins, Diana Conrad, Michael Coroneos, Nicholas Downie, David Floate, Peter Gates, Kerryn Green, Erwin Groeneveld, John Harrison Show all

MULTIPLE SCLEROSIS JOURNAL | SAGE PUBLICATIONS LTD | Published : 2019

Abstract

BACKGROUND: The evidence associating diet and risk of multiple sclerosis is inconclusive. OBJECTIVE: We investigated associations between dietary patterns and risk of a first clinical diagnosis of central nervous system demyelination, a common precursor to multiple sclerosis. METHODS: We used data from the 2003-2006 Ausimmune Study, a case-control study examining environmental risk factors for a first clinical diagnosis of central nervous system demyelination, with participants matched on age, sex and study region. Using data from a food frequency questionnaire, dietary patterns were identified using principal component analysis. Conditional logistic regression models (n = 698, 252 cases, 44..

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