Journal article

Etiologies and characteristics of refractory status epilepticus cases in different areas of the world: Results from a global audit

Monica Ferlisi, Sara Hocker, Eugen Trinka, Simon Shorvon

EPILEPSIA | WILEY | Published : 2018


To describe the demographics, etiologies, types of status epilepticus (SE), and outcomes in people with refractory and super-refractory SE from around the world, we prospectively collected cases of refractory SE (RSE) treated with continuous intravenous anesthetic drugs in an intensive care unit setting through online questionnaires using "active surveillance." We collected information about 776 cases of RSE in 50 countries over 4 years. Control of SE was achieved in 74% of the cases. Neurologic outcomes were poor in 41% of patients, and 24% died. Good outcome was associated with younger age and a history of epilepsy. Etiology strongly influenced the outcome. Patients from Asia were younger,..

View full abstract