Journal article

Arterial Structure and Function Following Viral Myocarditis

Asha Jois, Diana Zannino, Nigel Curtis, Michael Cheung, David P Burgner, Katherine YH Chen

Pediatric Cardiology | SPRINGER | Published : 2019


Acute viral myocarditis is an uncommon inflammatory disease of the myocardium. Little is known about the long-term cardiovascular risk for individuals who have recovered from the acute illness. We compared intermediate vascular phenotypes relating to arterial structure (aortic and carotid intima-media thickness) and function (pulse wave velocity, carotid arterial distensibility and compliance) in 15 participants, a median of 9.1 years after an episode of acute viral myocarditis, and 45 control participants. Following adjustment for age, sex and triglycerides, there were no differences in mean and maximum carotid and aortic intima-media thickness, pulse wave velocity, carotid artery distensib..

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Funding Acknowledgements

Katherine YH Chen holds an Australian Government Research Training Program scholarship from The University of Melbourne and a Postgraduate Health Research Scholarship from Murdoch Children's Research Institute. David P Burgner holds a National Health and Medical Research Council (NHMRC) Senior Research Fellowship and an honorary National Heart Foundation Future Leader Fellowship. Research at Murdoch Children's Research Institute is supported by the Victorian Government's Operational Infrastructure Support Program. The sponsors had no involvement in the study design, collection, analysis, interpretation, or in the writing of this manuscript.