Journal article

Trabecular bone score in adults with cerebral palsy

A Trinh, P Wong, MC Fahey, PR Ebeling, PJ Fuller, F Milat

BONE | ELSEVIER SCIENCE INC | Published : 2018

Abstract

CONTEXT: Bone fragility in cerebral palsy (CP) is secondary to a complex interplay of functional, hormonal, and nutritional factors that affect bone remodelling. A greater understanding of bone microarchitectural changes seen in CP should assist therapeutic decision making. OBJECTIVE: To examine the relationship between trabecular bone score (TBS), BMD and fractures in adults with CP; the influence of clinical factors and body composition on bone microarchitecture were explored. DESIGN: Retrospective cross-sectional study. SETTING AND PARTICIPANTS: 43 adults (25 male) with CP of median age 25 years (interquartile range 21.4-33.9) who had evaluable dual-energy X-ray absorptiometry imaging of ..

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Grants

Funding Acknowledgements

This research is supported by a Cerebral Palsy Alliance Research Foundation Grant. AT is supported by a Research Training Program scholarship from the Australian Government. FM is supported by an Endocrine Society of Australia Ken Wynne Post-Doctoral Grant. PW is supported by an NHMRC Early Career Fellowship. Hudson Institute is supported by the Victorian Government's Operational Infrastructure Support program.