Journal article

Potassium control in chronic kidney disease: implications for neuromuscular function

Ria Arnold, Timothy J Pianta, Bruce A Pussell, Zoltan Endre, Matthew C Kiernan, Arun V Krishnan

INTERNAL MEDICINE JOURNAL | WILEY | Published : 2019

Abstract

In Australia, approximately 1.7 million adults have evidence of chronic kidney disease (CKD). This complex disease can result in a multitude of complications, including hyperkalaemia, which is common and well recognised. The advent of new therapeutics aimed at lowering serum potassium has raised the possibility of optimising potassium control to enable greater use of renin-angiotensin-aldosterone system inhibitors in the management of CKD. Recent studies suggest that hyperkalaemia also has implications for peripheral neuropathy in CKD, a complication that substantially contributes to patient morbidity. This review examines evidence of the relationship between potassium and peripheral neuropa..

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University of Melbourne Researchers

Grants

Awarded by National Health and Medical Research Council of Australia


Awarded by Early Career Post-Doctoral Fellowship of the National Health and Medical Research Council of Australia


Awarded by National Health and Medical Research Council of Australia Program Grant


Funding Acknowledgements

A. V. Krishnan was supported by a Career Development Award of the National Health and Medical Research Council of Australia (grant number 1065663). R. Arnold was supported by an Early Career Post-Doctoral Fellowship of the National Health and Medical Research Council of Australia (#1091006). M. C. Kiernan was funded by Forefront, a collaborative research group supported from the National Health and Medical Research Council of Australia Program Grant (#1037746).