Journal article

Medical Management of Rheumatic Heart Disease: A Systematic Review of the Evidence

E Anne Russell, Warren F Walsh, Ben Costello, Alex JA McLellan, Alex Brown, Christopher M Reid, Lavinia Tran, Graeme P Maguire

Cardiology in Review | LIPPINCOTT WILLIAMS & WILKINS | Published : 2018


Rheumatic heart disease (RHD) is an important cause of heart disease globally. Its management can encompass medical and procedural (catheter and surgical) interventions. Literature pertaining to the medical management of RHD from PubMed 1990-2016 and via selected article reference lists was reviewed. Areas included symptom management, left ventricular dysfunction, rate control in mitral stenosis, atrial fibrillation, anticoagulation, infective endocarditis prophylaxis, and management in pregnancy. Diuretics, angiotensin blockade and beta-blockers for left ventricular dysfunction, and beta-blockers and If inhibitors for rate control in mitral stenosis reduced symptoms and improved left ventri..

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Funding Acknowledgements

Supported by NHMRC Centres for Research Excellence to Reduce Inequality in Heart Disease; End RHD and the Victorian Government's OIS Program; and The Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS). National Cardiac Surgery Database Program was funded by the Department of Health Victoria, the Health Administration Corporation, and the Clinical Excellence Commission (CEC) NSW. Funds were received from individual units.A.R. receives an NHMRC Postgraduate Scholarship and an Australian Government Research Training Program Scholarship. G.M. receives an NHMRC Practitioner Fellowship. C.R. receives an NHMRC Senior Research Fellowship. A.B. receives a Viertel Senior Medical Research Fellowship. A.M. receives a post-doctoral fellowship from the National Heart Foundation of Australia.