Short-term outcome of first episode delusional disorder in an early intervention population
Tobias Rowland, Maximillian Birchwood, Swaran Sing, Nicholas Freemantle, Linda Everard, Peter Jones, David Fowler, Tim Amos, Max Marshall, Vimal Sharma, Andrew Thompson
SCHIZOPHRENIA RESEARCH | ELSEVIER SCIENCE BV | Published : 2019
BACKGROUND: Previous evidence suggests that delusional disorder has a later onset and better functional outcomes compared to schizophrenia. However, studies have not examined longitudinal outcomes in a first episode population, where confounding factors may be adjusted for. METHODS: A nested case control study was designed within the National EDEN study; a cohort of 1027 first episode psychosis patients. Patients with a baseline diagnosis of delusional disorder (n = 48) were compared with schizophrenia (n = 262) at 6 and 12 months with respect to symptomatic and functional outcomes. Regression analysis was used to adjust for possible confounders. RESULTS: Delusional disorder patients had a s..View full abstract
Awarded by UK Department of Health
Awarded by National Institute of Health Research (NIHR) under the Programme Grants for Applied Research Programme
This work was supported by grants from the UK Department of Health (RDD/ARF2) and the National Institute of Health Research (NIHR) under the Programme Grants for Applied Research Programme (RP-PG-0109-10074). The views expressed in this publication are those of the authors and not necessarily those of the NHS, NIHR or the Department of Health. Professors Birchwood and Singh are part funded by the National Institute for Health Research (NIHR) through the Collaborations for Leadership in Applied Health Research and Care for West Midlands (CLAHRC-WM). Professor Jones is part funded by the NIHR CLAHRC East of England. Doctor Rowland is partly funded through the NIHR as an academic clinical fellow.