Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data

LS Román; BK Menon; J Blasco; M Hernández-Pérez; A Dávalos; CBLM Majoie; BCV Campbell; F Guillemin; HF Lingsma; R Anxionnat; J Epstein; JL Saver; HA Marquering; JH Wong; DK Lopes; G Reimann; H Desal; DWJ Dippel; S Coutts; R du Mesnil de Rochemont; DR Yavagal; JC Ferre; YBWEM Roos; DS Liebeskind; R Lenthall; CA Molina; FS Al Ajlan; V Reddy; D Dowlatshahi; S Nader-Antoine; C Oppenheim; AP Mitha; SM Davis; C Weimar; RJ van Oostenbrugge; E Cobo; TJ Kleinig; GA Donnan; A van der Lugt; AM Demchuk; OA Berkhemer; AMM Boers; GA Ford; KW Muir; BS Brown; TG Jovin; WH van Zwam; PJ Mitchell; MD Hill; P White; S Bracard; M Goyal

Journal article

Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data

LS Román, BK Menon, J Blasco, M Hernández-Pérez, A Dávalos, CBLM Majoie, BCV Campbell, F Guillemin, HF Lingsma, R Anxionnat, J Epstein, JL Saver, HA Marquering, JH Wong, DK Lopes, G Reimann, H Desal, DWJ Dippel, S Coutts, R du Mesnil de Rochemont Show all

Lancet Neurology | Published : 2018

DOI: 10.1016/S1474-4422(18)30242-4

Open access

Abstract

Background: Evidence regarding whether imaging can be used effectively to select patients for endovascular thrombectomy (EVT) is scarce. We aimed to investigate the association between baseline imaging features and safety and efficacy of EVT in acute ischaemic stroke caused by anterior large-vessel occlusion. Methods: In this meta-analysis of individual patient-level data, the HERMES collaboration identified in PubMed seven randomised trials in endovascular stroke that compared EVT with standard medical therapy, published between Jan 1, 2010, and Oct 31, 2017. Only trials that required vessel imaging to identify patients with proximal anterior circulation ischaemic stroke and that used predo..

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