Journal article

P2X7 Receptors Regulate Phagocytosis and Proliferation in Adult Hippocampal and SVZ Neural Progenitor Cells: Implications for Inflammation in Neurogenesis

Hannah C Leeson, Maria A Kasherman, Tailoi Chan-Ling, Michael D Lovelace, Jeremy C Brownlie, Kelly M Toppinen, Ben J Gu, Michael W Weible

Stem Cells | WILEY | Published : 2018


Awarded by National Health and Medical Research Council (NHMRC) of Australia

Awarded by ARC Future Fellowship

Awarded by NHMRC Project

Funding Acknowledgements

This work was supported by grants from the Rebecca L. Cooper Medical Research Foundation to M.W., T.C.L., and M.L., and to T.C.L. from the National Health and Medical Research Council (NHMRC) of Australia (571100 and 1048082) and the Baxter Charitable Foundation (Sydney, Australia). B.G. was supported by ARC Future Fellowship (BG, FT120100581), NHMRC Project Grants (1048082, 1061419, and 1120095) and the Victorian Government's Operational Infrastructure Support Grant to the Florey Institute. M.L. was supported by a Charles D. Kelman, M.D. Postdoctoral Award (2010) from the International Retinal Research Foundation (USA). Microglial cultures were kindly donated by the Clem Jones Centre for Neurobiology and Stem Cell Research, Brisbane Australia. The authors thank Maria Nguyen (Griffith Institute for Drug Discovery) for advice regarding microscopy, and Dr Xin Huang (Florey Institute of Neuroscience and Mental Health) for assistance with flow cytometry experiments.