P2X7 Receptors Regulate Phagocytosis and Proliferation in Adult Hippocampal and SVZ Neural Progenitor Cells: Implications for Inflammation in Neurogenesis
Hannah C Leeson, Maria A Kasherman, Tailoi Chan-Ling, Michael D Lovelace, Jeremy C Brownlie, Kelly M Toppinen, Ben J Gu, Michael W Weible
Stem Cells | WILEY | Published : 2018
Related Projects (2)
Awarded by National Health and Medical Research Council (NHMRC) of Australia
Awarded by ARC Future Fellowship
Awarded by NHMRC Project
This work was supported by grants from the Rebecca L. Cooper Medical Research Foundation to M.W., T.C.L., and M.L., and to T.C.L. from the National Health and Medical Research Council (NHMRC) of Australia (571100 and 1048082) and the Baxter Charitable Foundation (Sydney, Australia). B.G. was supported by ARC Future Fellowship (BG, FT120100581), NHMRC Project Grants (1048082, 1061419, and 1120095) and the Victorian Government's Operational Infrastructure Support Grant to the Florey Institute. M.L. was supported by a Charles D. Kelman, M.D. Postdoctoral Award (2010) from the International Retinal Research Foundation (USA). Microglial cultures were kindly donated by the Clem Jones Centre for Neurobiology and Stem Cell Research, Brisbane Australia. The authors thank Maria Nguyen (Griffith Institute for Drug Discovery) for advice regarding microscopy, and Dr Xin Huang (Florey Institute of Neuroscience and Mental Health) for assistance with flow cytometry experiments.