Journal article

Prospective outcome of early intervention for individuals at ultra-high-risk for psychosis

GeumSook Shim, Do-Hyung Kang, Jung-Seok Choi, Myung Hun Jung, Soo Jin Kwon, Go Eun Jang, Jun Soo Kwon

EARLY INTERVENTION IN PSYCHIATRY | WILEY | Published : 2008

Abstract

AIM: Based on previous reports of second-generation antipsychotic agents having a beneficial effect on prodromal symptoms, we investigated the effectiveness and tolerability of atypical antipsychotic therapies in individuals at high risk for developing psychosis. METHODS: We examined prodromal symptoms and functioning in individuals at ultra-high-risk for psychosis using an uncontrolled prospective design with pre- and post-treatment measures. RESULTS: Of the 27 subjects taking antipsychotics during the study period, 15 took part in at least one follow-up assessment. Overall Comprehensive Assessment of At-Risk Mental States scores significantly improved at the last evaluation point, with a m..

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University of Melbourne Researchers