Journal article

Mycobacterium ulcerans disease management in Australian patients: the re-emergence of surgery as an important treatment modality

Daniel P O'Brien, Peter Callan, N Deborah Friedman, Eugene Athan, Andrew Hughes, Anthony McDonald

ANZ JOURNAL OF SURGERY | WILEY | Published : 2019

Abstract

With the demonstration of the effectiveness of antibiotic treatment, the management of Mycobacterium ulcerans disease has changed from a predominantly surgically to a predominantly medically treated disease. However, research among Australian patients has revealed that antibiotic treatment alone is associated with prolonged wound healing times, high rates of treatment toxicity, and the potential for significant tissue destruction associated with severe paradoxical reactions. We present the current state of M. ulcerans management in Barwon Health, Australia, where a close working relationship exists between the Plastic Surgical and Infectious Diseases units. Here treatment has evolved based o..

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