Journal article

Prenatal diagnosis of closed spina bifida: multicenter case series and review of the literature.

Hérbene José Figuinha Milani, Enoch Quinderé de Sá Barreto, La Hong Chau, Nguyen Ha To, Antonio Fernandes Moron, Simon Meagher, Fabricio Da Silva Costa, Edward Araujo Júnior

J Matern Fetal Neonatal Med | Published : 2020


Objective: Closed spina bifida (CSB) is an abnormality of the posterior arch formation in which the defect is covered by the skin, without protrusion of nervous tissue. The prenatal diagnosis of CSB is very difficult, rarely diagnosed antenatally.Methods: We present a multicenter case series of six prenatal diagnosis of CSB using two-dimensional (2D) ultrasonography complemented with three-dimensional (3D) ultrasonography and magnetic resonance imaging (MRI). All cases of prenatal diagnosis of CSB were confirmed in the postnatal period/termination of pregnancy by both clinical and/or imaging diagnosis (ultrasonography and MRI).Results: 2D ultrasonography allowed the prenatal diagnosis of six..

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