Journal article

Assessment of the efficacy of an autogenous vaccine against Yersinia pseudotuberculosis in young Merino sheep

KJ Stanger, H McGregor, M Marenda, JM Morton, JWA Larsen



AIMS To assess the efficacy of an autogenous vaccine against Yersinia pseudotuberculosis III in preventing clinical disease and deaths due to yersiniosis in young Merino sheep, and to determine the effect of vaccination on the prevalence of faecal shedding of pathogenic Yersinia spp., daily liveweight gain, and development of antibodies to Yersinia spp. following vaccination and natural exposure. METHODS In six groups (three groups each from two farms) of young Merino sheep, 148-150 animals were systematically allocated to be vaccinated twice with an autogenous, formalin- killed bacterin vaccine containing Y. pseudotuberculosis serotype III or to remain non-vaccinated. All vaccinated and non..

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Awarded by Meat and Livestock Australia

Funding Acknowledgements

This study was supported by Meat and Livestock Australia (grant B.STU.0247) and the Scobie and Claire Mackinnon Trust. The authors gratefully acknowledge D Rees and other staff from the Mackinnon Project for their technical assistance, as well as the farm owners and managers who generously donated their time and facilities for this study. We would also like to express our gratitude to R Bushell and R Batey for their assistance with microbiology and antibiotic sensitivity testing. Dr Kelly Stanger received an Australian Postgraduate Award to support her involvement in this study.