Current surgical practice in pediatric ulcerative colitis: A systematic review

Abstract

Background: Surgical management of adult ulcerative colitis (UC) is well-studied, but not readily applicable to children. Restorative proctocolectomy with ileal pouch-anal anastomosis (RPC-IPAA), performed as one-, two-, or three-stage procedure, is preferred in pediatric patients with adequate anal sphincter function. Purpose: 1) Compare the outcomes of surgical management in pediatric UC. 2) Identify factors influencing choice of staged procedures for RPC-IPAA, and their associated complications (including pouch failure rates). Methods: Systematic review of Cochrane Register of Controlled Trials, PubMed, and EMBASE databases was conducted (January 1987–December 2016), in accordance with PR..