Operant Protocols for Assessing the Cost-benefit Analysis During Reinforced Decision Making by Rodents
Mojtaba Kermani, Zahra Fatahi, Dechuan Sun, Abbas Haghparast, Chris French
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS | JOURNAL OF VISUALIZED EXPERIMENTS | Published : 2018
Reinforcement-guided decision making is the ability to choose between competing courses of action based on the relative value of the benefits and their consequences. This process is integral to the normal human behavior and has been shown to be disrupted by neurological and psychiatric disorders such as addiction, schizophrenia, and depression. Rodents have long been used to uncover the neurobiology of human cognition. To this end, several behavioral tasks have been developed; however, most are non-automated and are labor-intensive. The recent development of the open-source microcontroller has enabled researchers to automate operant-based tasks for assessing a variety of cognitive tasks, sta..View full abstract
This research was supported by RMH Neuroscience Foundation, Australia; the Australian Brain Foundation; the RACP Thyne Reid Fellowship, Australia; and by a project grant from the Cognitive Sciences and Technologies Council, Iran to Abbas Haghparast.