Journal article

Breaking up sitting time after stroke (BUST-stroke)

C English, H Janssen, G Crowfoot, R Callister, A Dunn, P Mackie, C Oldmeadow, LK Ong, K Palazzi, AJ Patterson, NJ Spratt, FR Walker, J Bernhardt, DW Dunstan

International Journal of Stroke | SAGE PUBLICATIONS LTD | Published : 2018

Abstract

Objectives: People with stroke sit for long periods each day, which may compromise blood glucose control and increase risk of recurrent stroke. Studies in other populations have found regular activity breaks have a significant immediate (within-day) positive effect on glucose metabolism. We examined the effects of breaking up uninterrupted sitting with frequent, short bouts of light-intensity physical activity in people with stroke on post-prandial plasma glucose and insulin. Methods: Randomized within-participant crossover trial. We included people between 3 months and 10 years post-stroke, ambulant with minimal assistance and not taking diabetic medication other than metformin. The three e..

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University of Melbourne Researchers

Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The trial was supported by a Stroke Foundation of Australia Seeding Grant (2015) and John Hunter Hospital Charitable Trust Grant (2016). Associate Professor English was supported by National Heart Foundation Future Leaders Fellowship (2017-2020). Prof Dunstan was supported by an NHMRC Senior Research Fellowship (NHMRC #1078360). Prof Bernhardt was supported by a National Health and Medical Research Council Established Research Fellowship (#1058635). The Florey Institute of Neuroscience and Mental Health and Baker Institute acknowledge infrastructure support from the Victorian State Government. The results of this trial are presented clearly, honestly, and without fabrication, falsification, or inappropriate data manipulation.