Anti-hypercholesterolemic and anti-hyperglycaemic effects of conventional and supercritical extracts of black cumin (Nigella sativa)
Muhammad Jawad Iqbal, Masood Sadiq Butt, Mir Muhammad Nasir Qayyum, Hafiz Ansar Rasul Suleria
ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE | WOLTERS KLUWER MEDKNOW PUBLICATIONS | Published : 2017
Objective To explore the hypoglycaemic and hypocholesterolemic potential of conventional and supercritical extracts of black cumin. Methods Purposely, rat modelling was carried out for 2 months by designing three studies i.e. study I (normal rats), study II (hyperglycaemic rats) and study III (hypercholesterolemic rats). Each study was further divided into three groups based on diet i.e. control, functional diet (contained extract of black cumin prepared by using conventional solvent) and nutraceutical diet (contained extract of black cumin prepared by supercritical fluid extraction system). Results During whole trial, an abating trend was observed in the level of serum cholesterol with maxi..View full abstract
Awarded by Higher Education Commission
This research project was partially supported by Higher Education Commission, Pakistan under Pak-US Science and Technology Cooperation Program Phase IV (Project Grant No. 10/01/10-09/30/12), project entitled "Establishment of Functional and Nutraceutical Food Research Section at the National Institute of Food Science and Technology, University of Agriculture, Faisalabad, Pakistan".