Journal article

In vitro Anti-Thrombotic Activity of Extracts from Blacklip Abalone (Haliotis rubra) Processing Waste

Hafiz Ansar Rasul Suleria, Barney M Hines, Rama Addepalli, Wei Chen, Paul Masci, Glenda Gobe, Simone A Osborne

MARINE DRUGS | MDPI AG | Published : 2017

Abstract

Waste generated from the processing of marine organisms for food represents an underutilized resource that has the potential to provide bioactive molecules with pharmaceutical applications. Some of these molecules have known anti-thrombotic and anti-coagulant activities and are being investigated as alternatives to common anti-thrombotic drugs, like heparin and warfarin that have serious side effects. In the current study, extracts prepared from blacklip abalone (Haliotis rubra) processing waste, using food grade enzymes papain and bromelain, were found to contain sulphated polysaccharide with anti-thrombotic activity. Extracts were found to be enriched with sulphated polysaccharides and ass..

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Funding Acknowledgements

Hafiz Ansar Rasul Suleria was awarded an International Postgraduate Research Scholarship (IPRS), Australia Postgraduate Award (APA) and Postgraduate Studentship (Commonwealth Scientific and Industrial Research Organisation, CSIRO) from the Australian Government at the University of Queensland, Australia. This research received funding from the Fisheries Research and Development Corporation for initial work, which is sponsored by the Australian Government.