Association of Somatic Driver Alterations With Prognosis in Postmenopausal, Hormone Receptor-Positive, HER2-Negative Early Breast Cancer A Secondary Analysis of the BIG 1-98 Randomized Clinical Trial
Stephen J Luen, Rebecca Asher, Chee Khoon Lee, Peter Savas, Roswitha Kammler, Patrizia Dell'Orto, Olivia Maria Biasi, David Demanse, Lellean JeBailey, Sinead Dolan, Wolfgang Hackl, Beat Thuerlimann, Giuseppe Viale, Marco Colleoni, Meredith M Regan, Sherene Loi
JAMA Oncology | AMER MEDICAL ASSOC | Published : 2018
Awarded by Susan G. Komen for the Cure
This translational research was funded in part by Novartis (partial funding of tissue block collection and full funding of next-generation sequencing at Foundation Medicine) and Susan G. Komen for the Cure Promise Grant (nucleic acid extraction, grant KG080081 to Drs Viale and Regan). The Breast International Group (BIG) 1-98 trial was supported by Novartis. The International Breast Cancer Study Group (IBCSG), which coordinated the BIG 1-98 trial, was also supported by The Swedish Cancer Society, The Swedish Research Council, The Cancer Council Australia, Australia and New Zealand Breast Cancer Trials Group, Frontier Science and Technology Research Foundation, Swiss Group for Clinical Cancer Research, Cancer Research Switzerland/Oncosuisse, and the Foundation for Clinical Cancer Research of Eastern Switzerland. Dr Luen is supported by the University of Melbourne. Prof Loi is supported by Breast Cancer Research Foundation of Australia and the John Colebatch Cancer Council Victoria Clinical fellowship.