Conference Proceedings

Association between diabetic retinopathy and incident cognitive impairment

Preeti Gupta, Alfred TL Gan, Ryan Man, Eva Fenwick, Charumathi Sabanayagam, Christopher Li-Hsian Chen, NV Ramani, Xin Xu, Saima Hilal, Tien-Yin Wong, Ching-Yu Cheng, Ecosse L Lamoureux

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2018

Abstract

BACKGROUND/AIM: The relationship between diabetic retinopathy (DR) and cognitive impairment (CI) is unclear due to equivocal findings from cross-sectional studies and a lack of long-term data. In this population-based cohort study, we investigated the longitudinal association between the severity of DR and the incidence of CI. METHODS: 682 participants with diabetes, gradable retinal photographs and no CI at baseline 2004-2011) and complete relevant data at follow-up 2010-2016 from the Singapore Epidemiology of Eye Disease Study were included. CI was assessed using the validated Abbreviated Mental Test (AMT), defined as scores of ≤6 and ≤8 for those with 0-6 and >6 years of formal education,..

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