Journal article
Clinical outcome and risk factors for failure in late acute prosthetic joint infections treated with debridement and implant retention
M Wouthuyzen-Bakker, M Sebillotte, J Lomas, A Taylor, EB Palomares, O Murillo, J Parvizi, N Shohat, JC Reinoso, RE Sánchez, M Fernandez-Sampedro, E Senneville, K Huotari, JM Barbero, J Garcia-Cañete, J Lora-Tamayo, MC Ferrari, D Vaznaisiene, E Yusuf, C Aboltins Show all
Journal of Infection | W B SAUNDERS CO LTD | Published : 2019
Abstract
Objectives: Debridement, antibiotics and implant retention (DAIR) is the recommended treatment for all acute prosthetic joint infections (PJI), but its efficacy in patients with late acute (LA) PJI is not well described. Methods: Patients diagnosed with LA PJI between 2005 and 2015 were retrospectively evaluated. LA PJI was defined as the development of acute symptoms (≤ 3 weeks) occurring ≥ 3 months after arthroplasty. Failure was defined as: (i) the need for implant removal, (ii) infection related death, (iii) the need for suppressive antibiotic therapy and/or (iv) relapse or reinfection during follow-up. Results: 340 patients from 27 centers were included. The overall failure rate was 45...
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