Journal article

Reticular pseudodrusen: current understanding

Antony J Wightman, Robyn H Guymer

Clinical and Experimental Optometry | WILEY | Published : 2019

Abstract

Reticular pseudodrusen (RPD), also known as subretinal drusenoid deposits, represent a morphological change to the retina distinct from other subtypes of drusen by being located above the level of the retinal pigment epithelium. Although they can infrequently appear in individuals with no other apparent pathology, their highest rates of occurrence are in association with age-related macular degeneration (AMD), for which they hold clinical significance by being highly correlated with end-stage disease sub-types, choroidal neovascularisation and geographic atrophy. Reticular pseudodrusen are also found in other diseases, most notably Sorsby's fundus dystrophy, pseudoxanthoma elasticum and acqu..

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Grants

Awarded by National Health and Medical Research Council (NHMRC) Fellowship


Funding Acknowledgements

Supported by National Health and Medical Research Council (NHMRC) Fellowship (#1103013, RHG). The Centre for Eye Research Australia (CERA) receives Operational Infrastructure Support from the Victorian Government, Australia.