Transcription-factor-mediated supervision of global genome architecture maintains B cell identity

Timothy M Johanson; Aaron TL Lun; Hannah D Coughlan; Tania Tan; Gordon K Smyth; Stephen L Nutt; Rhys S Allan

Journal article

Transcription-factor-mediated supervision of global genome architecture maintains B cell identity

Timothy M Johanson, Aaron TL Lun, Hannah D Coughlan, Tania Tan, Gordon K Smyth, Stephen L Nutt, Rhys S Allan

Nature Immunology | NATURE PUBLISHING GROUP | Published : 2018

DOI: 10.1038/s41590-018-0234-8

University of Melbourne Researchers

Stephen Nutt Author Medical Biology (W.E.H.I.)

Rhys Allan Author Medical Biology (W.E.H.I.)

Hannah Coughlan Author Medical Biology (W.E.H.I.)

Tim Johanson Author Medical Biology (W.E.H.I.)

Gordon Smyth Author Mathematics and Statistics

Grants

Awarded by National Health and Medical Research Council of Australia

Awarded by Australian Research Council

Funding Acknowledgements

We thank T. Mason for animal husbandry and N. Iannarella for technical support. This work was supported by grants and fellowships from the National Health and Medical Research Council of Australia (S.L.N., 1054925 and 1058238; G.K.S., 1058892; A.T.L.L. and G.K.S., 1054618; R.S.A. and T.M.J., 1049307 and 1100451; T.M.J., 1124081) and the Australian Research Council (R.S.A., 130100541). This study was made possible through the Victorian State Government Operational Infrastructure Support and Australian Government NHMRC Independent Research Institute Infrastructure Support scheme.