Journal article

Social motivational processing and interpersonal function in aging cocaine smokers

Gillinder Bedi, Xuejun Hao, Nicholas T Van Dam, Ziva D Cooper, Eric Rubin, Nehal P Vadhan, Leslie Marino, Margaret Haney

ADDICTION BIOLOGY | WILEY | Published : 2019

Abstract

Illicit drug use among aging cohorts is increasing, yet little is known about functional impairments in older drug users. Given the importance of social integration for aging and documented social decrements in cocaine users, we examined social function and its neurocognitive substrates in aging cocaine users relative to carefully matched non-cocaine users. Regular (≥twice/week), long-term (≥15 years) cocaine smokers 50-60 years old (COCs; n = 22; four women) and controls (CTRLs; n = 19; four women) underwent standardized probes of social reward and threat processing during functional magnetic resonance imaging and a behavioral facial affect recognition task. Self-report and peer-report of d..

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