Effect of 1-h moderate-intensity aerobic exercise on intramyocellular lipids in obese men before and after a lifestyle intervention
Stephanie Ipavec-Levasseur, Ilaria Croci, Stephane Choquette, Nuala M Byrne, Gary Cowin, Trisha M O'Moore-Sullivan, Johannes B Prins, Ingrid J Hickman
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM | CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS | Published : 2015
Intramyocellular lipids (IMCL) are depleted in response to an acute bout of exercise in lean endurance-trained individuals; however, it is unclear whether changes in IMCL content are also seen in response to acute and chronic exercise in obese individuals. We used magnetic resonance spectroscopy in 18 obese men and 5 normal-weight controls to assess IMCL content before and after an hour of cycling at the intensity corresponding with each participant's maximal whole-body rate of fat oxidation (Fatmax). Fatmax was determined via indirect calorimetry during a graded exercise test on a cycle ergometer. The same outcome measures were reassessed in the obese group after a 16-week lifestyle interve..View full abstract
Awarded by NHMRC Health Research Partnership Grant
We acknowledge the assistance of Rachel Colley, Anais D'Arcy, Amy Davis, Matthew Meredith, Kathryn Nolan, and Darren Roffey. This study was funded by a NHMRC Health Research Partnership Grant (no. 264418) and by a Lions Medical Research Fellowship, Australia. Ingrid Hickman was funded by an NHMRC Australian Clinical Research Fellow grant.