Total body fat and the risk of Barrett's oesophagus - A bioelectrical impedance study
Bradley J Kendall, Graeme A Macdonald, Johannes B Prins, Suzanne O'Brien, David C Whiteman
CANCER EPIDEMIOLOGY | ELSEVIER SCI LTD | Published : 2014
BACKGROUND: Body mass index is associated with the risk of Barrett's oesophagus (BO). It is uncertain whether this is related to total body fat or other factors that correlate with body mass index. We aimed to quantify the association between total body fat (measured by bioelectrical impedance) and risk of BO and examine if this association was modified by gastro-oesophageal reflux (GOR) and abdominal obesity. METHODS: In 2007-2009, we surveyed 235 cases (69% Males, Mean age 62.1 years) and 244 age and sex matched population controls from a population based case-control study of BO. We conducted structured interviews, standard anthropometry and bioimpedance analysis of total body fat. Odds r..View full abstract
Awarded by Queensland Cancer Fund
Awarded by National Cancer Institute
Awarded by NATIONAL CANCER INSTITUTE
This study was funded by grants by the Queensland Cancer Fund (Grant 442962) and, Queensland Government Smart State Fund. The SDH was funded by the National Cancer Institute (Grant RO1 CA 001833). DCW is supported by a Future Fellowship from the Australia Research Council. The funding bodies played no role in the design or conduct of the study; the collection, management, analysis, or interpretation of the data; or preparation, review, or approval of the manuscript.