The risk of Barrett's esophagus associated with abdominal obesity in males and females
Bradley J Kendall, Graeme A Macdonald, Nicholas K Hayward, Johannes B Prins, Suzanne O'Brien, David C Whiteman
INTERNATIONAL JOURNAL OF CANCER | WILEY-BLACKWELL | Published : 2013
Esophageal adenocarcinoma arises from Barrett's esophagus (BE). Both occur predominantly in males. The role of abdominal obesity in this sex distribution is uncertain. Our study aimed to determine whether there is an association between abdominal obesity and risk of BE and if present was it modified by sex. A structured interview and anthropometric measures were conducted within a population-based case-control study. We recruited 237 BE cases (70% male) and 247 population controls, frequency matched by age and sex. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using multivariable logistic regression analysis. In the overall group and males, all measures of abdominal obes..View full abstract
Awarded by National Cancer Institute
Awarded by NATIONAL CANCER INSTITUTE
Grant sponsor: Queensland Cancer Fund, Queensland Government Smart State Fund and National Cancer Institute (Grant RO1 CA 001833).