Adiponectin is associated with cardiovascular disease in male renal transplant recipients: baseline results from the LANDMARK 2 study
Mohd O Kaisar, Kirsty Armstrong, Carmel Hawley, Scott Campbell, David Mudge, David W Johnson, John B Prins, Nicole M Isbel
BMC Nephrology | BMC | Published : 2009
BACKGROUND: Adiponectin is a major adipocyte-derived protein with insulin-sensitizing, anti-inflammatory and anti-atherogenic properties. Adiponectin levels correlate inversely with renal function and higher levels are predictive of lower cardiovascular disease (CVD) in patients with normal renal function and chronic kidney disease. No data exists on the association between adiponectin and CVD in renal transplant recipients (RTR). METHODS: Standard biochemistry, clinical data and adiponectin were collected from 137 RTR recruited to the LANDMARK 2 study at baseline. The LANDMARK 2 study is an ongoing randomized controlled study that compares the outcome of aggressive risk factor modification ..View full abstract
This study was funded by the Centre for Clinical Research and Excellence, National Health and Medical Research Council.