Changes in serum prolactin, sex hormones and thyroid function with alternate nightly nocturnal home haemodialysis
Carolyn van Eps, Carmel Hawley, Janine Jeffries, David W Johnson, Scott Campbell, Nicole Isbel, David W Mudge, Johannes Prins
NEPHROLOGY | WILEY | Published : 2012
AIM: Uraemia is associated with hyperprolactinaemia, low total (TT) and free (FT) serum testosterone, high luteinizing hormone (LH) and follicle-stimulating hormone (FSH) and, in women, anovulatory cycles and premature menopause. We hypothesize that extended hours haemodialysis may improve these derangements. METHODS: This is an observational cohort study of 30 men (age 54±13 years, body mass index (BMI) 28.1±5.8 kg/m2) and seven women (age 41±11 years, BMI 32.2±11.2 kg/m2) established on chronic home haemodialysis (3-5 h, 3.5-5 sessions weekly) who were converted to nocturnal home haemodialysis (6-9 h, 3.5-5 sessions weekly). Serum was collected at baseline and 6 months for measurement of T..View full abstract
We gratefully acknowledge our funding source (The National Health and Medical Research Council of Australia), the nursing and technical staff of the Princess Alexandra Hospital Home Haemodialysis Unit and our patients. Authors on this paper have received travel and research grants and fees for lectures from Fresenius Medical Care, Baxter and Gambro. Carmel Hawley and David Johnson have been members of the advisory boards for Fresenius Medical care, Baxter and Gambro.