Journal article

Aging per se does not influence glucose homeostasis - In vivo and in vitro evidence

P Imbeault, JB Prins, M Stolic, AW Russell, T O'Moore-Sullivan, JP Despres, C Bouchard, A Tremblay

DIABETES CARE | AMER DIABETES ASSOC | Published : 2003

Abstract

OBJECTIVE: To assess the effect of age on glucose metabolism by examining 1) glucose metabolism in young and middle-aged subjects when total or regional adiposity is taken into account and 2) in vitro glucose transport in adipose tissue explants from young and middle-aged women paired for total and abdominal adiposity. RESEARCH DESIGN AND METHODS: Study 1: body composition, subcutaneous abdominal and visceral adipose tissue areas, and fasting and oral glucose-stimulated glucose and insulin were measured in 84 young and 81 middle-aged men and in 110 young and 91 middle-aged women. Study 2: glucose uptake in subcutaneous abdominal and visceral adipose tissue explants were measured in eight you..

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University of Melbourne Researchers