Journal article

Should an oral glucose tolerance test be performed routinely in all renal transplant recipients?

Kirsten A Armstrong, Johannes B Prins, Elaine M Beller, Scott B Campbell, Carmel M Hawley, David W Johnson, Nicole M Isbel

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | AMER SOC NEPHROLOGY | Published : 2006

Abstract

Posttransplantation diabetes (PTD) contributes to cardiovascular disease and graft loss in renal transplant recipients (RTR). Current recommendations advise fasting blood glucose (FBG) as the screening and diagnostic test of choice for PTD. This study sought to determine (1) the predictive power of FBG with respect to 2-h blood glucose (2HBG) and (2) the prevalence of PTD using FBG and 2HBG compared with that using FBG alone, in prevalent RTR. A total of 200 RTR (mean age 52 yr; 59% male; median transplant duration 6.6 yr) who were > 6 mo posttransplantation and had no known history of diabetes were studied. Patients with FBG or = 200 mg/dl [11.1 mmol/L]) and impaired glucose tolerance (IGT..

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University of Melbourne Researchers