Journal article

Sex-Dependent Effects of Environmental Enrichment on Spatial Memory and Brain-Derived Neurotrophic Factor (BDNF) Signaling in a Developmental "Two-Hit" Mouse Model Combining BDNF Haploinsufficiency and Chronic Glucocorticoid Stimulation

Adrienne M Grech, Udani Ratnayake, Anthony J Hannan, Maarten van den Buuse, Rachel A Hill

Frontiers in Behavioral Neuroscience | FRONTIERS MEDIA SA | Published : 2018

DOI: 10.3389/fnbeh.2018.00227

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Modeling early intervention in schizophrenia: role of BDNF

Schizophrenia is a major burden on sufferers and society at large. Currently available treatments are only partially effective and often ass..

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Awarded by NHMRC Project

Awarded by NHMRC Principal Research Fellowship

Funding Acknowledgements

This study was supported by an NHMRC Project Grant to MvdB, AH, and RH (GNT1044777). AH is supported by an NHMRC Principal Research Fellowship (GNT1117148).

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Keywords

Hippocampus
Trkb
Factor-Expression
Neurosciences & Neurology
Spatial Memory
Depression
Life Sciences & Biomedicine
Prefrontal Cortex
Neurosciences
Stress
Behavioral Sciences
Corticosterone
Neuroplasticity
Cognitive Deficits
Environmental Enrichment
Brain-Derived Neurotrophic Factor
Corticosterone Treatment
Science & Technology
Schizophrenia
Mice Implications