Journal article
Clinical trial participation by adolescents and young adults with cancer: A continued cause for concern?
V White, G Skaczkowski, A Anazodo, H Bibby, W Nicholls, R Pinkerton, K Thompson, LM Orme, R Conyers, M Osborn, MB Phillips, R Harrup, R Walker, M Coory
Seminars in Oncology | W B SAUNDERS CO-ELSEVIER INC | Published : 2018
Abstract
International data indicate that rates of clinical trial enrolment for Adolescents and Young Adults (AYAs) with cancer are markedly lower than for any other age group. This paper reviews the recent literature reporting international trends in clinical trial enrolment since 2010. Subsequently, we present the first population-based, national assessment of clinical trial enrolment for AYAs with cancer in Australia. Reported rates of trial enrolment from Australia, Canada, the United States, and the United Kingdom were variable, though consistently low, ranging between 2% and 29%. Trial enrolment was higher for younger AYAs (typically 15–19 years) and those attending pediatric hospitals, and thi..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This work was supported by a National Health and Medical Research Council of Australia (NHMRC) project grant 1012250 and grants from CanTeen and The Kids' Cancer Project. The funders had no role in the study design, collection or interpretation of data, the writing of the report or the decision to submit the manuscript for publication.