Alzheimer's Disease: Toward a Quantitative Biological Approach in Describing its Natural History and Underlying Mechanisms. Toward a Quantitative Biological Approach in Describing its Natural History and Underlying Mechanisms.
CL Masters, B Gu, S Laws, YY Lim, B Roberts, VL Villemagne, K Beyreuther
The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms | Published : 2018
Alzheimer's disease remains a major therapeutic challenge despite a massive research effort over the past two decades. Applying quantitative mechanistic approaches to understanding the quantities and rates of Aβ amyloid production, accumulation and clearance may provide novel and more rigorous insights into developing rational therapeutic strategies.