Book Chapter

Alzheimer's Disease: Toward a Quantitative Biological Approach in Describing its Natural History and Underlying Mechanisms. Toward a Quantitative Biological Approach in Describing its Natural History and Underlying Mechanisms.

CL Masters, B Gu, S Laws, YY Lim, B Roberts, VL Villemagne, K Beyreuther

The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms | Published : 2018

Abstract

Alzheimer's disease remains a major therapeutic challenge despite a massive research effort over the past two decades. Applying quantitative mechanistic approaches to understanding the quantities and rates of Aβ amyloid production, accumulation and clearance may provide novel and more rigorous insights into developing rational therapeutic strategies.

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