Journal article

Functional network connectivity is altered in patients with upper limb somatosensory impairments in the acute phase post stroke: A cross-sectional study

Nele De Bruyn, Sarah Meyer, Simon S Kessner, Bea Essers, Bastian Cheng, Goetz Thomalla, Andre Peeters, Stefan Sunaert, Thierry Duprez, Vincent Thijs, Hilde Feys, Kaat Alaerts, Geert Verheyden



BACKGROUND: Aberrant functional connectivity in brain networks associated with motor impairment after stroke is well described, but little is known about the association with somatosensory impairments. AIM: The objective of this cross-sectional observational study was to investigate the relationship between brain functional connectivity and severity of somatosensory impairments in the upper limb in the acute phase post stroke. METHODS: Nineteen first-ever stroke patients underwent resting-state functional magnetic resonance imaging (rs-fMRI) and a standardized clinical somatosensory profile assessment (exteroception and higher cortical somatosensation) in the first week post stroke. Integrit..

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Awarded by Scientific Research Flanders (FWO)

Awarded by Promobilia Foundation

Awarded by German Research Foundation

Funding Acknowledgements

This work was supported by Scientific Research Flanders (FWO) [grant number 1189817N] (ND) and [grant number 1518814N] (SM); the Promobilia Foundation [grant number 15060](SM); the Foundation Van Goethem Brichant (SM); the German Research Foundation [grant number SFB 936 - project C2](SK; GT; BC). All funding sources have no involvement in the conduct of the research and preparation of the article.