Functional network connectivity is altered in patients with upper limb somatosensory impairments in the acute phase post stroke: A cross-sectional study
Nele De Bruyn, Sarah Meyer, Simon S Kessner, Bea Essers, Bastian Cheng, Goetz Thomalla, Andre Peeters, Stefan Sunaert, Thierry Duprez, Vincent Thijs, Hilde Feys, Kaat Alaerts, Geert Verheyden
PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2018
BACKGROUND: Aberrant functional connectivity in brain networks associated with motor impairment after stroke is well described, but little is known about the association with somatosensory impairments. AIM: The objective of this cross-sectional observational study was to investigate the relationship between brain functional connectivity and severity of somatosensory impairments in the upper limb in the acute phase post stroke. METHODS: Nineteen first-ever stroke patients underwent resting-state functional magnetic resonance imaging (rs-fMRI) and a standardized clinical somatosensory profile assessment (exteroception and higher cortical somatosensation) in the first week post stroke. Integrit..View full abstract
Awarded by Scientific Research Flanders (FWO)
Awarded by Promobilia Foundation
Awarded by German Research Foundation
This work was supported by Scientific Research Flanders (FWO) [grant number 1189817N] (ND) and [grant number 1518814N] (SM); the Promobilia Foundation [grant number 15060](SM); the Foundation Van Goethem Brichant (SM); the German Research Foundation [grant number SFB 936 - project C2](SK; GT; BC). All funding sources have no involvement in the conduct of the research and preparation of the article.