Response inhibition and interference control in obsessive-compulsive spectrum disorders
Laura S van Velzen, Chris Vriend, Stella J de Wit, Odile A van den Heuvel
FRONTIERS IN HUMAN NEUROSCIENCE | FRONTIERS MEDIA SA | Published : 2014
Over the past 20 years, motor response inhibition and interference control have received considerable scientific effort and attention, due to their important role in behavior and the development of neuropsychiatric disorders. Results of neuroimaging studies indicate that motor response inhibition and interference control are dependent on cortical-striatal-thalamic-cortical (CSTC) circuits. Structural and functional abnormalities within the CSTC circuits have been reported for many neuropsychiatric disorders, including obsessive-compulsive disorder (OCD) and related disorders, such as attention-deficit hyperactivity disorder, Tourette's syndrome, and trichotillomania. These disorders also sha..View full abstract
Awarded by Netherlands Organization for Scientific Research (NWO-ZonMw VENT grant)
This article was supported by a NARSAD young investigator award of the Brain and Behavior Research Foundation granted to Dr. Odile A. van den Heuvel and a grant from the Netherlands Organization for Scientific Research (NWO-ZonMw VENT grant 916.86.036, Dr. Odile A. van den Heuvel).